Holderness posted a recent snap of herself with Sir David to Twitter on the weekend, much to the delight of fans.
The 73-year-used actress captioned the shot of the pair smiling together: “So lovely to be with Sir DJ again.”
Holderness is best known for her role as Marlene Boyce on the iconic display, while Sir David’s role as cockney market trader Derek ‘Del Boy’ Trotter made him a household brand.
The pair had bumped into each other at the annual Only Fools And Horses convention in Milton Keynes over the weekend.
They were joined by former display producer Adrian Pegg and director Tony Dow.
As well as Only Fools And Horses, Holderness has appeared on spin-off display The Green Green Grass from 2005 to 2009.
She also starred on the likes of Doctors, Still Open All Hours and EastEnders.
Sir David also had starring roles in Open All Hours and A Touch of Frost, and the more recently axed sitcom Still Open All Hours.